MDMA is an abbreviation for 3,4-methylenedioxymethamphetamine or methylenedioxy-methylamfetamine. In pill form, it is commonly referred to as ecstasy or Molly. MDMA has recently emerged as a potential treatment for post-traumatic stress disorder (PTSD) when combined with psychotherapy.

MDMA has been a popular illicit substance at parties and raves for decades. It tends to induce feelings of euphoria, altered senses, and increased empathy. The effects of MDMA can last for hours.


MDMA has a reputation for making people feel energetic, happy, and in the mood to connect and share with others. In patients with PTSD, these feelings may help them feel willing to share their traumatic experiences and work through them with a competent guide.

Studies indicate MDMA could produce striking improvements in PTSD symptoms when combined with talk therapy.

It’s important to note that MDMA, when taken as a street drug, will not yield effective PTSD treatment. MDMA treatment should only be pursued with a certified specialist in a safe and carefully controlled setting.

A significant body of clinical research focuses on MDMA’s potential for PTSD treatment. Some researchers believe that MDMA’s antidepressant-like effects may be effective in the treatment of depression and anxiety related to life-threatening illnesses. However, additional clinical research is needed to determine the long-term effectiveness of MDMA for depression, anxiety, and other mood disorders.

Recreational MDMA may be combined with other drugs and contaminated with other substances. The MDMA used in trials is clinical-grade. Taking too much MDMA can result in serious complications, including heart problems, strokes, and seizures.